Avantages
The pay is good and the company is usually sound. There is opportunity for advancement and you are clearly expected to gain experience and climb the corporate ladder. "Dead weight" seems to get cut when the inevitable lay-offs occur, which in my experience has been every 3 years or so. As big pharma companies go, Roche is ethical and patient safety is a big issue. Work life balance is also encouraged, but I find it ironic that when you drive by late at night or on a weekend, it's not management's Mercedes or BMW's in the parking lot, it's the rank and file.
Inconvénients
Corporate bureaucracy is a huge problem. It's like working for the federal government. Roche is so big and there are so many different division and acquisitions, communication is horrible and efficiency is effected. It can take days just to get a simple computer issue solved.